scale_x_continuous() and scale_y_continuous() can change how the axis is plotted. Can use the breaks argument to specify how you want the axis ticks to be.
range(pull(Orange, circumference))
[1]  30 214
range(pull(Orange, age))
[1]  118 1582
plot_scale <-ggplot(Orange, aes(x = circumference, y = age)) +
                geom_point(size = 5, color = "red", alpha = 0.5) +
                geom_line(size = 0.8, color = "brown", linetype = 2) +
                scale_x_continuous(breaks = seq(from = 20, to = 240, by = 20)) +
                scale_y_continuous(breaks = seq(from = 100, to = 1600, by = 200))